In this wacky detective story, a postal worker adopts a new puppy that delights his girlfriend and her son. Little do they know, the dog was formerly a trained FBI drug-sniffer and was an important witness to a crime. When a pair of hit men come around, trying to assassinate the dog, SEE SPOT RUN explodes into a comic kaleidoscope of outrageous gags and near-escapes reminiscent of HOME ALONE.