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The Design and Development of Novel Drugs and Vaccines: Principles and Protocols
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Numero oggetto eBay:196332391386
Specifiche dell'oggetto
- Condizione
- ISBN
- 9780128214718
- Publication Year
- 2021
- Type
- Textbook
- Format
- Trade Paperback
- Language
- English
- Subject Area
- Business & Economics, Medical
- Publication Name
- Design and Development of Novel Drugs and Vaccines : Principles and Protocols
- Publisher
- Elsevier Science & Technology
- Item Length
- 9 in
- Subject
- Clinical Medicine, Industries / Pharmaceutical & Biotechnology, Pharmacology
- Item Width
- 6 in
- Number of Pages
- 320 Pages
Informazioni su questo prodotto
Product Identifiers
Publisher
Elsevier Science & Technology
ISBN-10
0128214716
ISBN-13
9780128214718
eBay Product ID (ePID)
2321073331
Product Key Features
Number of Pages
320 Pages
Publication Name
Design and Development of Novel Drugs and Vaccines : Principles and Protocols
Language
English
Publication Year
2021
Subject
Clinical Medicine, Industries / Pharmaceutical & Biotechnology, Pharmacology
Type
Textbook
Subject Area
Business & Economics, Medical
Format
Trade Paperback
Dimensions
Item Length
9 in
Item Width
6 in
Additional Product Features
Intended Audience
Scholarly & Professional
TitleLeading
The
Reviews
"I have read other books on clinical research, but none with the level of detail and particular focus on drug design (the computational drug design sections) that this one has. This book is very detailed-oriented from that standpoint, and it can certainly serve as a useful tool for those developing vaccines." --© Doody's Review Service, 2021, Patrick J Scoble, PharmD(PJS Pharma Consulting LLC), reviewer, expert opinion
Table Of Content
1. Introduction of structural bioinformatics with respect to drug discovery 2. Target identification and validation 3. Retrieval of compounds 4. Lead identification and optimization 5. Molecular dynamics simulations 6. An overview of vaccine design 7. Key steps in the selection of vaccine targets 8. Epitope prediction and selection of linkers and adjuvant 9. Design of vaccine constructs 10. In-silico validation through protein-protein docking 11. Molecular cloning 12. Protein expression 13. Protein purification and desalting 14. Biological assay 15. Biophysical methods 16. Outline of animal study for lead/ vaccine testing 17. Evaluation of immunogenicity of vaccine candidate 18. In-vitro evaluation of lead molecule 19. Medical physiological parameter for lead/vaccine testing 20. Brief introduction of clinical research and trials 21. An overview of IND, NDA, approval agencies and FDA post-marketing surveillance 22. Introduction of Intellectual property rights
Synopsis
The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval.
LC Classification Number
RM301.25
Descrizione dell'oggetto fatta dal venditore
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