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Chemical Reagents for Protein Modification by Roger L. Lundblad (2014, Hardcover)

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Chemical Reagents for Protein Modification, Hardcover by Lundblad, Roger L., ISBN 146657190X, ISBN-13 9781466571907, Brand New, Free shipping in the US Unlike the two previous editions, says Lundblad, this fourth is substantially revised and enlarged, though chemical modification of proteins is not as popular now as when the first edition was published in 1983. He begins with the reagents and processes: alkylating agents, acylating agents, nitration and nitrosylation, oxidation, and modifying proteins with reducing agents. Then he surveys the chemical modification of various proteins: cysteine, cystine, methionine, carboxyl groups in proteins, tyrosine residues, tryptophan, amino groups, histidine, and arginine. Annotation ©2014 Ringgold, Inc., Portland, OR ()

Informazioni su questo prodotto

Product Identifiers

PublisherCRC Press LLC

ISBN-10146657190X

ISBN-139781466571907

eBay Product ID (ePID)20038387178

Product Key Features

Number of Pages684 Pages

LanguageEnglish

Publication NameChemical Reagents for Protein Modification

Publication Year2014

SubjectLife Sciences / Molecular Biology, Pharmacology, Biochemistry, Chemistry / Organic, Chemistry / General

FeaturesNew Edition

TypeTextbook

AuthorRoger L. Lundblad

Subject AreaScience, Medical

FormatHardcover

Dimensions

Item Height1.7 in

Item Weight47.3 Oz

Item Length10.2 in

Item Width7.2 in

Additional Product Features

Edition Number4

Intended AudienceScholarly & Professional

Dewey Edition22

IllustratedYes

Dewey Decimal572.6

Table Of ContentIntroduction to the Chemical Modification of Proteins Alkylating Agents Acylating Agents Nitration and Nitrosylation Oxidation Modification of Proteins with Reducing Agents Chemical Modification of Cysteine Chemical Modification of Cystine Modification of Methionine Modification of Carboxyl Groups in Proteins Modification of Tyrosine Residues Modification of Tryptophan Modification of Amino Groups Modification of Histidine Modification of Arginine

Edition DescriptionNew Edition

SynopsisThe use of the chemical modification of proteins has evolved over the past 80 years, benefiting from advances in analytical, physical, and organic chemistry. Over the past 30 years, the use of chemical reagents to modify proteins has been crucial in determining the function and structure of purified proteins. This groundbreaking work is part of the foundation of emerging disciplines of proteomics, chemical biology, structure biology, and chemical proteomics. Chemical Reagents for Protein Modification, Fourth Edition provides a comprehensive review of reagents used for the chemical modification of proteins, representing a major revision of the work presented in previous editions. The completely updated Fourth Edition is substantially larger and includes five new chapters: Alkylating Agents Acylating Agents Nitration and Nitrosylation Oxidation Modification of Proteins with Reducing Agents There is greatly increased coverage of the chemical modification of cysteine, which is critical for bioconjugate synthesis. The chapter on reduction also provides information necessary for bioconjugate synthesis as well as for the processing of inclusion bodies. The book places emphasis on conditions that affect the specificity of the chemical modification of proteins, such as solvent and temperature. The format has been markedly revised, presenting information based on the chemical nature of the modifying material and on the amino acid residue modified. This new version has increased significance to biopharmaceuticals. Much of the information is in tabular form, which enables the rapid location of cited material.

LC Classification NumberQP551.L88 2014