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Mechanisms of Adiponectin Action by Tania Fiaschi: New
US $58,77
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Oggetto che si trova a: Sparks, Nevada, Stati Uniti
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Numero oggetto eBay:365317305510
Specifiche dell'oggetto
- Condizione
- Book Title
- Mechanisms of Adiponectin Action
- Publication Date
- 2019-07-26
- Pages
- 222
- ISBN
- 9783039212453
Informazioni su questo prodotto
Product Identifiers
Publisher
Mdpi A&G
ISBN-10
3039212451
ISBN-13
9783039212453
eBay Product ID (ePID)
21038643045
Product Key Features
Number of Pages
222 Pages
Language
English
Publication Name
Mechanisms of Adiponectin Action
Subject
General
Publication Year
2019
Type
Textbook
Subject Area
Medical
Format
Trade Paperback
Dimensions
Item Height
0.6 in
Item Weight
17 Oz
Item Length
9.6 in
Item Width
6.7 in
Additional Product Features
Intended Audience
Trade
Illustrated
Yes
Synopsis
The adipokine adiponectin is very concentrated in plasma, and decreased levels of adiponectin are associated with pathological conditions such as obesity, diabetes, cardiovascular diseases, and metabolic syndrome. When produced in its full-length form, adiponectin self-associates to generate multimeric complexes. The full-length form of adiponectin can be cleaved by the globular form of elastase that is produced locally, and the resulting biological effects are exerted in a paracrine or autocrine manner. The different forms of adiponectin bind to specific receptors consisting of two G-protein-independent, seven-transmembrane-spanning receptors, called AdipoR1 and AdipoR2, while T-cadherin has been identified as a potential receptor for high molecular weight complexes of adiponectin. Adiponectin exerts a key role in cellular metabolism, regulating glucose levels as well as fatty acid breakdown. However, its biological effects are heterogeneous, involving multiple target tissues. The Special Issue "Mechanisms of Adiponectin Action" highlights the pleiotropic role of this hormone through 3 research articles and 7 reviews. These papers focus on the recent knowledge regarding adiponectin in different target tissues, both in healthy and in diseased conditions.
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