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Ion Channels of Excitable Membranes by Bertil Hille: Used

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Specifiche dell'oggetto

Condizione
Buone condizioni: Libro che è già stato letto ma è in buone condizioni. Mostra piccolissimi danni ...
Book Title
Ion Channels of Excitable Membranes
Publication Date
2001-07-16
Edition Number
3
Pages
816
ISBN
9780878933211

Informazioni su questo prodotto

Product Identifiers

Publisher
Oxford University Press, Incorporated
ISBN-10
0878933212
ISBN-13
9780878933211
eBay Product ID (ePID)
1947497

Product Key Features

Number of Pages
814 Pages
Publication Name
Ion Channels of Excitable Membranes
Language
English
Publication Year
2001
Subject
Neuroscience, Life Sciences / Cell Biology, General
Type
Textbook
Subject Area
Science, Psychology, Medical
Author
Bertil Hille
Format
Hardcover

Dimensions

Item Height
1.3 in
Item Weight
50.1 Oz
Item Length
9.6 in
Item Width
6.9 in

Additional Product Features

Edition Number
3
Intended Audience
College Audience
LCCN
2001-032776
Dewey Edition
21
Reviews
"The third edition of Ion Channels of Excitable Membranes is markedly expanded, remarkably up to date, and stands as an unmitigated tour de force. Complete and enthusiastic, but not overwhelming, the text builds intuitively from the biophysical roots of the discipline. By maintaining a historical flavor, the reader is cleanly offered the essential ideas and concepts that remain key even as the field evolves. The book remains a resource forpractitioners of the craft and the essential guide to the electrophysiological universe." --Steven A. N. Goldstein, Cell, "The third edition of Ion Channels of Excitable Membranes is markedly expanded, remarkably up to date, and stands as an unmitigated tour de force. Complete and enthusiastic, but not overwhelming, the text builds intuitively from the biophysical roots of the discipline. By maintaining a historical flavor, the reader is cleanly offered the essential ideas and concepts that remain key even as the field evolves. The book remains a resource for practitioners of the craft and the essential guide to the electrophysiological universe." --Steven A. N. Goldstein, Cell
Illustrated
Yes
Dewey Decimal
57106/4
Table Of Content
1. IntroductionPART I: Description of Channels2. Classical Biophysics of the Squid Giant Axon3. The Superfamily of Voltage-Gated Channels4. Voltage-Gated Calcium Channels5. Potassium Channels and Chloride Channels6. Ligand-Gated Channels of Fast Chemical Synapses7. Modulation, Slow Synaptic Action, and Second Messengers8. Sensory Transduction and Excitable Cells9. Calcium Dynamics, Epithelial Transport, and Intercellular CouplingPART II: Principles and Mechanisms of Functions10. Elementary Properties of Ions in Solution11. Elementary Properties of Pores12. Counting Channels and Measuring Fluctuations13. Structure of Channel Proteins14. Selective Permeability: Independence15. Selective Permeability: Saturation and Binding16. Classical Mechanisms of Block17. Structure-Function Studies of Permeation and Block18. Gating Mechanisms: Kinetic Thinking19. Gating: Voltage Sensing and Inactivation20. Modification of Gating in Voltage-Sensitive Channels21. Cell Biology and Channels22. Evolution and Origins
Synopsis
This fully revised and expanded Third Edition of Ion Channels of Excitable Membranes describes the known channels and their physiological functions, then develops the conceptual background needed to understand their architecture and molecular mechanisms of operation. It includes new chapters on calcium signaling, structural biology, and molecular biology and genomics. Ion Channels of Excitable Membranes begins with the classical biophysical work of Hodgkin and Huxley, continues with the roles of channels in cellular signaling, then develops the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. It has long been the recognized authoritative overview of this field used by all neuroscientists., Ion channels underlie a broad range of the most basic biological processes, from excitation and signaling to secretion and absorption. Like enzymes, they are diverse and ubiquitous macromolecular catalysts with high substrate specificity and subject to strong regulation. This fully revised and expanded third edition of Ion Channels of Excitable Membranes describes the known channels and their physiological functions, then develops the conceptual background needed to understand their architecture and molecular mechanisms of operation. It includes new chapters on calcium signaling, structural biology, and molecular biology and genomics. Ion Channels of Excitable Membranes begins with the classical biophysical work of Hodgkin and Huxley, continues with the roles of channels in cellular signaling, then develops the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ion Channels of Excitable Membranes is written to be accessible and interesting to life scientists and physical scientists of all kinds. It introduces all the concepts that a graduate student should be aware of but is also effective in advanced undergraduate courses. It has long been the recognized authoritative overview of this field used by all neuroscientists., Published by Sinauer Associates, an imprint of Oxford University Press. Ion channels underlie a broad range of the most basic biological processes, from excitation and signaling to secretion and absorption. Like enzymes, they are diverse and ubiquitous macromolecular catalysts with high substrate specificity and subject to strong regulation. This fully revised and expanded third edition of Ion Channels of Excitable Membranes describes the known channels and their physiological functions, then develops the conceptual background needed to understand their architecture and molecular mechanisms of operation. It includes new chapters on calcium signaling, structural biology, and molecular biology and genomics. Ion Channels of Excitable Membranes begins with the classical biophysical work of Hodgkin and Huxley, continues with the roles of channels in cellular signaling, then develops the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ion Channels of Excitable Membranes is written to be accessible and interesting to life scientists and physical scientists of all kinds. It introduces all the concepts that a graduate student should be aware of but is also effective in advanced undergraduate courses. It has long been the recognized authoritative overview of this field used by all neuroscientists.
LC Classification Number
QH603.I54H54 2001

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