The TNF Superfamily Methods and Protocols 2nd Edition 2021 Hardcover Bayry

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Specifiche dell'oggetto

Condizione
Nuovo: Libro nuovo, intatto e non letto, in perfette condizioni, senza pagine mancanti o ...
ISBN
9781071611296

Informazioni su questo prodotto

Product Identifiers

Publisher
Springer
ISBN-10
1071611291
ISBN-13
9781071611296
eBay Product ID (ePID)
8050097772

Product Key Features

Edition
2
Book Title
Tnf Superfamily : Methods and Protocols
Number of Pages
Xiv, 284 Pages
Language
English
Publication Year
2020
Topic
Life Sciences / Molecular Biology, Life Sciences / Biochemistry
Illustrator
Yes
Genre
Science
Author
Jagadeesh Bayry
Book Series
Methods in Molecular Biology Ser.
Format
Hardcover

Dimensions

Item Weight
27 Oz
Item Length
10 in
Item Width
7 in

Additional Product Features

TitleLeading
The
Dewey Edition
23
Series Volume Number
2248
Number of Volumes
1 vol.
Dewey Decimal
616.079
Table Of Content
Signaling in TNFSF15-mediated Suppression of VEGF Production in Endothelial Cells.- Sensitization of Airway Epithelial Cells to Toxin-Induced Death by TNF Superfamily Cytokines.- Inhibition of Chondroitin Sulfate Proteoglycans by APRIL.- Induction of Antigen-independent Proliferation of Regulatory T-cells by TNF superfamily ligands OX40L and GITRL.- Transition from TNF-induced Inflammation to Death Signaling.- Analysis of Fc g R-Dependent Agonism Of Antibodies Specific for Receptors of the Tumor Necrosis Factor (TNF) Receptor Superfamily (TNFRSF).- Generation and Evaluation of Bispecific anti-TNF Antibodies Based on Single-Chain VHH Domains.- In Vitro Physical and Functional Interaction Assays to Examine the Binding of Progranulin Derivative Atsttrin to TNFR2 and its anti-TNFα activity.- Fluorescence Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators.- Production of Multi-Subtype Influenza Virus-Like Particles by Molecular Fusion with BAFF or APRIL for Vaccine Development.- Experimental Methods for the Immunological Characterization of Paradoxical Psoriasis Reactions Induced by TNF-α Biologics.- Methods for the Administration of EDAR Pathway Modulators in Mice.- Analysis of Ligand-Receptor Interactions Using Bioluminescent TNF Superfamily (TNFSF) Ligand Fusion Proteins.- Monitoring Atsttrin-mediated Inhibition of TNFα/NF-κβ Activation through in vivo Bioluminescence Imaging.- The use of Murine Infection Models to Investigate the Protective Role of TNF in Central Nervous System Tuberculosis.- Identification of CD137- and CD137L-expressing Cells in EL-4 Tumor.- -Expression Profiling of Tumor Necrosis Factor Superfamily Ligands mRNA in Healthy and Injured Murine Kidneys.- Analysis of Lymphotoxin Alpha Expression in Human Retina and Generation of Expression Vectors to Functional Characterization of Polymorphisms in the Tumor Necrosis Factor Locus.- Detection of TNF-α Protein in Extracellular Vesicles Derived from Tumor Cells by Western Blotting.- Expression of TNFRs by B and T lymphocytes in Tumor-Draining Lymph Nodes.- Methods for Evaluation of TNF-α Inhibition Effect.
Synopsis
This second edition focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Chapters detail protocols on the signaling process of TNF family members, technical examples to investigating the role of TNF family members in physiopathologies, modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, methodologies for various assays of TNF family members and the production of recombinant molecules. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, The TNF Superfamily: Methods and Applications, Second Edition serves to aid researchers investigating this key family of proteins.
LC Classification Number
QD431-431.7

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