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Cancer Drug Discovery and Development: DNA Repair in Cancer Therapy (2004, Hardc
US $39,00
CircaEUR 33,78
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Condizione:
“Book looks like new, in pristine condition with minimal making”
Buone condizioni
Libro che è già stato letto ma è in buone condizioni. Mostra piccolissimi danni alla copertina incluse alcune rigature, ma nessun foro o strappo. È possibile che la sovraccoperta per le copertine rigide non sia inclusa. La rilegatura presenta minimi segni di usura. La maggior parte delle pagine non è danneggiata e mostra una quantità minima di piegature o strappi, sottolineature di testo a matita, nessuna evidenziazione di testo né scritte ai margini. Non ci sono pagine mancanti. Per maggiori dettagli e la descrizione di eventuali imperfezioni, consulta l'inserzione del venditore.
- Compralo SubitoCancer Drug Discovery and Development: DNA Repair in Cancer Therapy (2004, Hardc
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Spedizione:
Gratis USPS Media MailTM.
Oggetto che si trova a: Reseda, California, Stati Uniti
Consegna:
Consegna prevista tra il ven 1 ago e il lun 4 ago a 94104
Restituzioni:
Restituzioni entro 30 giorni. Le spese di spedizione del reso sono a carico dell'acquirente..
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Numero oggetto eBay:122724777229
Specifiche dell'oggetto
- Condizione
- Buone condizioni
- Note del venditore
- “Book looks like new, in pristine condition with minimal making”
- ISBN
- 9781588292988
Informazioni su questo prodotto
Product Identifiers
Publisher
Humana Press
ISBN-10
1588292983
ISBN-13
9781588292988
eBay Product ID (ePID)
30452618
Product Key Features
Number of Pages
Xi, 363 Pages
Publication Name
D N A Repair in Cancer Therapy
Language
English
Publication Year
2004
Subject
Chemotherapy, Life Sciences / Genetics & Genomics, Oncology
Type
Textbook
Subject Area
Science, Medical
Series
Cancer Drug Discovery and Development Ser.
Format
Hardcover
Dimensions
Item Weight
54.7 Oz
Item Length
9.3 in
Item Width
6.1 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2003-017360
Dewey Edition
22
Reviews
...gives a comprehensive review of the modern status of the DNA repair field for cancer researchers and clinical practitioners and provides a solid basis for in-depth study of different areas in this field...The book is a timely publication with a significant intended audience that will be served well. The book is well planned, well written, comprehensive, and addresses recent findings in the field. -Doody's Health Sciences Book Review Journal"...extensive and extremely detailed...a comprehensive review of DNA repair." - The Annals of Pharmacotherapy"Comprehensive and cutting-edge, for both cancer researchers and practicing oncologists dealing with the hallmark 'relapse; or 'drug resistance' phenomena on a daily basis...." Tumori, ...gives a comprehensive review of the modern status of the DNA repair field for cancer researchers and clinical practitioners and provides a solid basis for in-depth study of different areas in this field...The book is a timely publication with a significant intended audience that will be served well. The book is well planned, well written, comprehensive, and addresses recent findings in the field. -Doody's Health Sciences Book Review Journal "...extensive and extremely detailed...a comprehensive review of DNA repair." - The Annals of Pharmacotherapy "Comprehensive and cutting-edge, for both cancer researchers and practicing oncologists dealing with the hallmark 'relapse; or 'drug resistance' phenomena on a daily basis...." Tumori
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
616.99/4061
Table Of Content
Content.- 1 Clinical Resistance to Alkylators: Status and Perspective.- 2 Role of Nonhomologous End-Joining and Recombinational DNA Repair in Resistance to Nitrogen Mustard and DNA Crosslinking Agents.- 3 Repair of DNA Interstrand Crosslinks Produced by Cancer Chemotherapeutic Drugs.- 4 Chemosensitization to Platinum-Based Anticancer Drugs: Current Trends and Future Prospects.- 5 Regulation of DNA Repair and Apoptosis by p53 and Its Impact on Alkylating Drug Resistance of Tumor Cells.- 6 Stress-Activated Signal Transduction Pathways in DNA Damage Response: Implications for Repair, Arrest, and Therapeutic Interventions.- 7 Overcoming Resistance to Alkylating Agents by Inhibitors of O6-Alkylguanine-DNA Alkyltransferase.- 8 Cellular Protection Against the Antitumor Drug Bleomycin.- 9 Potential Role of PARP Inhibitors in Cancer Treatment and Cell Death.- 10 Relationship Among DNA Repair Genes, Cellular Radiosensitivity, and the Response of Tumors and Normal Tissues to Radiotherapy.- 11 Strand-Break Repair and Radiation Resistance.- 12 V(D)J Recombination and DNA Double-Strand-Break Repair: From Immune Deficiency to Tumorigenesis.- 13 Inherited Disorders of Genomic Instability and Cancer Susceptibility.- 14 Role of BRCA1 and BRCA2 in DNA Repair and Potential Impact on Therapeutics.- 15 Genetic Variations in DNA Repair: Their Implications in Human Cancer Risk, Prevention, and Therapy.
Synopsis
This volume is concerned with the hallmark "relapse" or "drug resistance" phenomena that face the practicing oncologist on a daily basis. It covers the increasing evidence that impaired expression/activity of at least some of the DNA repair proteins account for tumor cell resistance to particular therapeutic agents. DNA Repair Therapeutics summarizes timely in-depth reviews covering the latest developments that have potential for translational and clinical applications and represents the first volume dedicated to the translational aspect of DNA repair in the clinic., A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.
LC Classification Number
RC254-282
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